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Research focus

CHIRI spans research from molecular, to cellular, to animal model and clinical activities, right through to epidemiological and population studies. Health innovation can therefore happen at any scale.


 CHIRI researchers

As an ‘adult only’ medical research institute, we are focussed on developing new treatments for the diseases that commonly occur with older age. Our approach to disease prevention and treatment is summarised in our ViNC research themes:

Vascular and metabolic disorders

The institute is identifying new treatments for age-associated blood vessel disorders, including bleeding and clotting disorders, heart disease, and stroke. We are also targeting blood vessel growth and function to treat age-associated cancers, blood-vessel inflammatory disorders with ageing, age-linked energy disorders, liver disorders, and age-associated infectious diseases

Immune disorders

Our research aims to stop the decline in immune function with ageing, target the immune system to treat adult cancers, and target immune function for treatment of infection and muscle repair.

Neurological disorders

We explore novel and new approaches for the prevention and treatment of Alzheimer’s disease and other dementias, as well as the prevention and treatment for neurodegenerative diseases such as multiple sclerosis and epilepsy.

Cancer

The institute is researching novel interventions for age-associated cancers such breast, pancreas, prostate, and melanoma. We are focusing on how the immune system influences cancer risk and progression and trialling novel interventions.